Collagen Stimulators

Collagen stimulators — also called biostimulators — trigger the body’s natural collagen production pathways for long-lasting skin rejuvenation that continues to improve for months after treatment. Unlike immediate-effect hyaluronic acid fillers, these injectables work by activating fibroblasts and stimulating neocollagenesis, resulting in progressive tissue quality improvement, volume restoration, and structural lift.

Our range includes PCL-based Richesse PCL for sustained collagen scaffolding, PDLLA-microsphere Aesthefill for volumetric biostimulation, and peptide-enriched Etrebelle formulations available in 50mg and 200mg concentrations for tailored treatment intensity.

Results typically become apparent from week 6 and continue developing over 6–12 months. Duration of effect commonly reported at 18–24 months. An increasingly preferred choice for patients seeking natural, gradual improvement without the immediate look of filler.